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Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease

Growing evidence supports a role for mitochondrial iron metabolism in the pathophysiology of neurodegenerative disorders such as Friedreich ataxia (FRDA) and Parkinson disease (PD) as well as in the motor and cognitive decline associated with the aging process. Iron–sulfur enzyme deficits and region...

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Detalhes bibliográficos
Autor principal: Isaya, Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939683/
https://ncbi.nlm.nih.gov/pubmed/24624085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00029
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