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Mitochondrial iron-sulfur cluster dysfunction in neurodegenerative disease

Growing evidence supports a role for mitochondrial iron metabolism in the pathophysiology of neurodegenerative disorders such as Friedreich ataxia (FRDA) and Parkinson disease (PD) as well as in the motor and cognitive decline associated with the aging process. Iron–sulfur enzyme deficits and region...

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Bibliographic Details
Main Author: Isaya, Grazia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939683/
https://ncbi.nlm.nih.gov/pubmed/24624085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00029
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