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The NFκB Antagonist CDGSH Iron-Sulfur Domain 2 Is a Promising Target for the Treatment of Neurodegenerative Diseases

Proinflammatory response and mitochondrial dysfunction are related to the pathogenesis of neurodegenerative diseases (NDs). Nuclear factor κB (NFκB) activation has been shown to exaggerate proinflammation and mitochondrial dysfunction, which underlies NDs. CDGSH iron-sulfur domain 2 (CISD2) has been...

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Foilsithe in:Int J Mol Sci
Main Authors: Kung, Woon-Man, Lin, Muh-Shi
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832822/
https://ncbi.nlm.nih.gov/pubmed/33477809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020934
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