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Photochemical Generation and Reactivity of the 5,6-Dihydrouridin-6-yl Radical

Nucleobase radicals are the major family of reactive intermediates formed when nucleic acids are exposed to hydroxyl radical, which is produced by γ-radiolysis and Fe • EDTA. Significant advances have been made in understanding the role of nucleobase radicals in oxidative DNA damage by independently...

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Dades bibliogràfiques
Publicat a:J Org Chem
Autors principals: Newman, Cory A., Resendiz, Marino J. E., Sczepanski, Jonathan T., Greenberg, Marc M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831383/
https://ncbi.nlm.nih.gov/pubmed/19691299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo9012805
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