Valproic Acid Treatment Rescues Injured Tissues After Traumatic Brain Injury

BACKGROUND: No agents that are specifically neuroprotective are currently approved to emergently treat patients with traumatic brain injury (TBI). The histone deacetylase inhibitor, high-dose valproic acid (VPA) has been shown to have cytoprotective potential in models of combined TBI and hemorrhagi...

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發表在:J Trauma Acute Care Surg
Main Authors: Biesterveld, Ben E., Pumiglia, Luke, Iancu, Ariella, Shamshad, Alizeh A., Remmer, Henriette A., Siddiqui, Ali Z., O’Connell, Rachel L., Wakam, Glenn K., Kemp, Michael T., Williams, Aaron M., Pai, Manjunath P., Alam, Hasan B.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830776/
https://ncbi.nlm.nih.gov/pubmed/32890344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002918
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