Valproic Acid Treatment Rescues Injured Tissues After Traumatic Brain Injury

BACKGROUND: No agents that are specifically neuroprotective are currently approved to emergently treat patients with traumatic brain injury (TBI). The histone deacetylase inhibitor, high-dose valproic acid (VPA) has been shown to have cytoprotective potential in models of combined TBI and hemorrhagi...

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Detalhes bibliográficos
Publicado no:J Trauma Acute Care Surg
Main Authors: Biesterveld, Ben E., Pumiglia, Luke, Iancu, Ariella, Shamshad, Alizeh A., Remmer, Henriette A., Siddiqui, Ali Z., O’Connell, Rachel L., Wakam, Glenn K., Kemp, Michael T., Williams, Aaron M., Pai, Manjunath P., Alam, Hasan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830776/
https://ncbi.nlm.nih.gov/pubmed/32890344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000002918
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