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Brain proteomic changes by histone deacetylase inhibition after traumatic brain injury

BACKGROUND: Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. There are currently no cytoprotective treatments for TBI. There is growing evidence that the histone deacetylase inhibitor valproic acid (VPA) may be beneficial in the treatment of TBI associated with hemorrhagic...

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Detalhes bibliográficos
Publicado no:Trauma Surg Acute Care Open
Main Authors: Pumiglia, Luke, Williams, Aaron M, Kemp, Michael T, Wakam, Glenn K, Alam, Hasan B, Biesterveld, Ben E
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993337/
https://ncbi.nlm.nih.gov/pubmed/33880414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/tsaco-2021-000682
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