Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury

Acute traumatic brain injury (TBI) is associated with long-term cognitive and behavioral dysfunction. In vivo studies have shown histone deacetylase inhibitors (HDACis) to be neuroprotective following TBI in rodent models. HDACis are intriguing candidates because they are capable of provoking widesp...

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Detalhes bibliográficos
Main Authors: Lu, Jie, Frerich, Jason M., Turtzo, L. Christine, Li, Siqi, Chiang, Jeffrey, Yang, Chunzhang, Wang, Xiaoping, Zhang, Chao, Wu, Chenxi, Sun, Zhongchan, Niu, Gang, Zhuang, Zhengping, Brady, Roscoe O., Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696796/
https://ncbi.nlm.nih.gov/pubmed/23754423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308950110
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