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Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability
DNA transcription and replication are two essential physiological processes that can turn into a threat for genome integrity when they compete for the same DNA substrate. During transcription, the nascent RNA strongly binds the template DNA strand, leading to the formation of a peculiar RNA–DNA hybr...
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| Published in: | Front Cell Dev Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7829580/ https://ncbi.nlm.nih.gov/pubmed/33505970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.618157 |
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