Filia is an ESC-specific regulator of DNA damage response and safeguards genomic stability

Pluripotent stem cells (PSCs) hold great promise in cell-based therapy, but the genomic instability seen in culture hampers full application. Greater understanding of the factors that regulate genomic stability in PSCs could help address this issue. Here we describe the identification of Filia as a...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Zhao, Bo, Zhang, Wei-dao, Duan, Ying-liang, Lu, Yong-qing, Cun, Yi-xian, Li, Chao-hui, Guo, Kun, Nie, Wen-hui, Li, Lei, Zhang, Rugang, Zheng, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610728/
https://ncbi.nlm.nih.gov/pubmed/25936915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.03.017
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