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PhenQE8, a Novel Ligand of the Human Telomeric Quadruplex †

A novel quadruplex ligand based on 1,10-phenanthroline and incorporating two guanyl hydrazone functionalities, PhenQE8, is reported herein. Synthetic access was gained in a two-step procedure with an overall yield of 61%. X-ray diffraction studies revealed that PhenQE8 can adopt an extended conforma...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Gratal, Patricia B., Quero, Julia G., Pérez-Redondo, Adrián, Gándara, Zoila, Gude, Lourdes
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828518/
https://ncbi.nlm.nih.gov/pubmed/33451070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020749
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