The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I

To prevent accumulation of misfolded proteins in the endoplasmic reticulum, chaperones perform quality control on newly translated proteins and redirect misfolded proteins to the cytosol for degradation by the ubiquitin-proteasome system. This pathway is called ER-associated protein degradation (ERA...

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Publicado no:Molecules
Main Authors: Schuren, A.B.C., Boer, I.G.J., Bouma, E.M., Van de Weijer, M.L., Costa, A.I., Hubel, P., Pichlmair, A., Lebbink, R.J., Wiertz, E.J.H.J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827699/
https://ncbi.nlm.nih.gov/pubmed/33430125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26020287
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