Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+ HCMV-specific cytotoxic T lymphocytes

BACKGROUND: To identify novel HLA-A*2402-restricted human cytomegalovirus (HCMV) immediate early-1 (IE-1) epitopes for adoptive immunotherapy, we explored 120 overlapping 15-amino acid spanning IE-1. METHODS: These peptides were screened by measuring the frequency of polyclonal CD8+ T cells producin...

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Main Authors: Lim, Jong-Baeck, Kim, Hyun Ok, Jeong, Seok Hoon, Ha, Joo Eun, Jang, Sunphil, Lee, Sang-Guk, Lee, Kyungwon, Stroncek, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739166/
https://ncbi.nlm.nih.gov/pubmed/19698161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-72
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