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DNA-Damage-Induced Alternative Splicing of p53

SIMPLE SUMMARY: The tumor suppressor p53 is frequently mutated across numerous cancer types and has an essential role in the response to DNA-damaging agents, such as irradiation. DNA damage can induce different forms of the p53 protein, and the different forms of the p53 protein can elicit distinct...

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Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Chen, Jing, Zhang, Dadong, Qin, Xiaodi, Owzar, Kouros, McCann, Jennifer J., Kastan, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827558/
https://ncbi.nlm.nih.gov/pubmed/33445417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020251
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