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HSP90α Mediates Sorafenib Resistance in Human Hepatocellular Carcinoma by Necroptosis Inhibition under Hypoxia

SIMPLE SUMMARY: Hypoxia is one of the characteristics of most solid tumors and induces cell resistant to chemotherapy. In this paper, we established a hypoxia model in both in vitro and in vivo to investigate the mechanisms of Sorafenib resistance in Hepatocellular carcinoma (HCC). Here, we observed...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Liao, Yan, Yang, Yue, Pan, Di, Ding, Youxiang, Zhang, Heng, Ye, Yuting, Li, Jia, Zhao, Li
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7827218/
https://ncbi.nlm.nih.gov/pubmed/33440739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020243
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