Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers

Platinum resistance seriously impacts on the survival outcomes of patients with ovarian cancers. Platinum-induced DNA damage is processed through DNA repair. NBS1 is a key DNA repair protein. Here, we evaluated the role of NBS1 in ovarian cancers. NBS1 expression was investigated in clinical cohorts...

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Udgivet i:Biomedicines
Main Authors: Alblihy, Adel, Alabdullah, Muslim L., Ali, Reem, Algethami, Mashael, Toss, Michael S., Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826685/
https://ncbi.nlm.nih.gov/pubmed/33435622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010056
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