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How Insertion of a Single Tryptophan in the N-Terminus of a Cecropin A-Melittin Hybrid Peptide Changes Its Antimicrobial and Biophysical Profile

In the era of antibiotic resistance, there is an urgent need for efficient antibiotic therapies to fight bacterial infections. Cationic antimicrobial peptides (CAMP) are promising lead compounds given their membrane-targeted mechanism of action, and high affinity towards the anionic composition of b...

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Bibliografiske detaljer
Udgivet i:Membranes (Basel)
Main Authors: Ferreira, Ana Rita, Teixeira, Cátia, Sousa, Carla F., Bessa, Lucinda J., Gomes, Paula, Gameiro, Paula
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826622/
https://ncbi.nlm.nih.gov/pubmed/33445476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes11010048
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