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How Insertion of a Single Tryptophan in the N-Terminus of a Cecropin A-Melittin Hybrid Peptide Changes Its Antimicrobial and Biophysical Profile

In the era of antibiotic resistance, there is an urgent need for efficient antibiotic therapies to fight bacterial infections. Cationic antimicrobial peptides (CAMP) are promising lead compounds given their membrane-targeted mechanism of action, and high affinity towards the anionic composition of b...

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Detalhes bibliográficos
Publicado no:Membranes (Basel)
Main Authors: Ferreira, Ana Rita, Teixeira, Cátia, Sousa, Carla F., Bessa, Lucinda J., Gomes, Paula, Gameiro, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826622/
https://ncbi.nlm.nih.gov/pubmed/33445476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes11010048
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