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Retro and retroenantio analogs of cecropin-melittin hybrids.

Hybrid analogs of cecropin A (CA) and melittin (M), which are potent antibacterial peptides, have been synthesized. To understand the structural requirements for this antibacterial activity, we have also synthesized the enantio, retro, and retroenantio isomers of two of the hybrids and their N-termi...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Merrifield, R B, Juvvadi, P, Andreu, D, Ubach, J, Boman, A, Boman, H G
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42184/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7724582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.8.3449
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