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Inhibition of MLKL Attenuates Necroptotic Cell Death in a Murine Cell Model of Hepatic Ischaemia Injury

Background: Steatosis in donor livers poses a major risk of organ dysfunction due to their susceptibility to ischaemia-reperfusion (I/R) injury during transplant. Necroptosis, a novel form of programmed cell death, is orchestrated by receptor-interacting protein kinase 1 (RIPK1), receptor-interactin...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Baidya, Raji, Gautheron, Jérémie, Crawford, Darrell H. G., Wang, Haolu, Bridle, Kim R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826539/
https://ncbi.nlm.nih.gov/pubmed/33435617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10020212
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