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Repositioning of histamine H(1) receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2

The spread of the corona virus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been intensifying in the past year, posing a huge threat to global health. There is an urgent need for effective drugs and vaccines to fight the COVID-19, but th...

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Publicado en:Eur J Pharmacol
Autores principales: Ge, Shuai, Wang, Xiangjun, Hou, Yajing, Lv, Yuexin, Wang, Cheng, He, Huaizhen
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier B.V. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826143/
https://ncbi.nlm.nih.gov/pubmed/33497607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2021.173897
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