Azelastine inhibits viropexis of SARS-CoV-2 spike pseudovirus by binding to SARS-CoV-2 entry receptor ACE2

A recent study have reported that pre-use of azelastine is associated with a decrease in COVID-19 positive test results among susceptible elderly people. Besides, it has been reported that antihistamine drugs could prevent viruses from entering cells. The purpose of this study is to investigate whet...

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Udgivet i:Virology
Main Authors: Ge, Shuai, Lu, Jiayu, Hou, Yajing, Lv, Yuexin, Wang, Cheng, He, Huaizhen
Format: Artigo
Sprog:Inglês
Udgivet: Published by Elsevier Inc. 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8144927/
https://ncbi.nlm.nih.gov/pubmed/34052578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2021.05.009
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