Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus

BACKGROUND: The novel coronavirus disease (2019-nCoV) has been affecting global health since the end of 2019 and there is no sign that the epidemic is abating . The major issue for controlling the infectious is lacking efficient prevention and therapeutic approaches. Chloroquine (CQ) and Hydroxychlo...

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Bibliografiske detaljer
Udgivet i:Phytomedicine
Main Authors: Wang, Nan, Han, Shengli, Liu, Rui, Meng, Liesu, He, Huaizhen, Zhang, Yongjing, Wang, Cheng, Lv, Yanni, Wang, Jue, Li, Xiaowei, Ding, Yuanyuan, Fu, Jia, Hou, Yajing, Lu, Wen, Ma, Weina, Zhan, Yingzhuan, Dai, Bingling, Zhang, Jie, Pan, Xiaoyan, Hu, Shiling, Gao, Jiapan, Jia, Qianqian, Zhang, Liyang, Ge, Shuai, Wang, Saisai, Liang, Peida, Hu, Tian, Lu, Jiayu, Wang, Xiangjun, Zhou, Huaxin, Ta, Wenjing, Wang, Yuejin, Lu, Shemin, He, Langchong
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier GmbH. 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467095/
https://ncbi.nlm.nih.gov/pubmed/32920291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phymed.2020.153333
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