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HIF in Nephrotoxicity during Cisplatin Chemotherapy: Regulation, Function and Therapeutic Potential

SIMPLE SUMMARY: Cisplatin is a widely used chemotherapy drug, but its use and efficacy are limited by its nephrotoxicity. HIF has protective effects against kidney injury during cisplatin chemotherapy, but it may attenuate the anti-cancer effect of cisplatin. In this review, we describe the role and...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Li, Siyao, Wen, Lu, Hu, Xiaoru, Wei, Qingqing, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825709/
https://ncbi.nlm.nih.gov/pubmed/33430279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020180
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