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Molecular and Biochemical Techniques for Deciphering p53-MDM2 Regulatory Mechanisms

The p53 and Mouse double minute 2 (MDM2) proteins are hubs in extensive networks of interactions with multiple partners and functions. Intrinsically disordered regions help to adopt function-specific structural conformations in response to ligand binding and post-translational modifications. Differe...

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Bibliografische gegevens
Gepubliceerd in:Biomolecules
Hoofdauteurs: Karakostis, Konstantinos, López, Ignacio, Peña-Balderas, Ana M., Fåhareus, Robin, Olivares-Illana, Vanesa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824699/
https://ncbi.nlm.nih.gov/pubmed/33396576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11010036
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