A single synonymous mutation determines the phosphorylation and stability of the nascent protein

p53 is an intrinsically disordered protein with a large number of post-translational modifications and interacting partners. The hierarchical order and subcellular location of these events are still poorly understood. The activation of p53 during the DNA damage response (DDR) requires a switch in th...

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Detalhes bibliográficos
Publicado no:J Mol Cell Biol
Main Authors: Karakostis, Konstantinos, Vadivel Gnanasundram, Sivakumar, López, Ignacio, Thermou, Aikaterini, Wang, Lixiao, Nylander, Karin, Olivares-Illana, Vanesa, Fåhraeus, Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6734142/
https://ncbi.nlm.nih.gov/pubmed/30252118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjy049
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