Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the formation of intracellular aggregate composed of heavily phosphorylated tau protein and extracellular deposit of amyloid-β (Aβ) plaques derived from proteolysis cleavage of amyloid precursor protein (APP). Autophagy refers to the lysosomal-mediated de...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines
Main Authors: Rahman, Md. Ataur, Rahman, Md Saidur, Rahman, MD. Hasanur, Rasheduzzaman, Mohammad, Mamun-Or-Rashid, ANM, Uddin, Md Jamal, Rahman, Md Rezanur, Hwang, Hongik, Pang, Myung-Geol, Rhim, Hyewhon
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824196/
https://ncbi.nlm.nih.gov/pubmed/33374126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items