Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by the formation of intracellular aggregate composed of heavily phosphorylated tau protein and extracellular deposit of amyloid-β (Aβ) plaques derived from proteolysis cleavage of amyloid precursor protein (APP). Autophagy refers to the lysosomal-mediated de...

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Dettagli Bibliografici
Pubblicato in:Biomedicines
Autori principali: Rahman, Md. Ataur, Rahman, Md Saidur, Rahman, MD. Hasanur, Rasheduzzaman, Mohammad, Mamun-Or-Rashid, ANM, Uddin, Md Jamal, Rahman, Md Rezanur, Hwang, Hongik, Pang, Myung-Geol, Rhim, Hyewhon
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7824196/
https://ncbi.nlm.nih.gov/pubmed/33374126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010005
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