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Modulatory Effects of Autophagy on APP Processing as a Potential Treatment Target for Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by the formation of intracellular aggregate composed of heavily phosphorylated tau protein and extracellular deposit of amyloid-β (Aβ) plaques derived from proteolysis cleavage of amyloid precursor protein (APP). Autophagy refers to the lysosomal-mediated de...
Uloženo v:
| Vydáno v: | Biomedicines |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7824196/ https://ncbi.nlm.nih.gov/pubmed/33374126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9010005 |
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