Discovery, Function, and Therapeutic Targeting of Siglec-8

Siglecs (sialic acid-binding immunoglobulin-like lectins) are single-pass cell surface receptors that have inhibitory activities on immune cells. Among these, Siglec-8 is a CD33-related family member selectively expressed on human mast cells and eosinophils, and at low levels on basophils. These cel...

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Dades bibliogràfiques
Publicat a:Cells
Autors principals: Youngblood, Bradford A., Leung, John, Falahati, Rustom, Williams, Jason, Schanin, Julia, Brock, Emily C., Singh, Bhupinder, Chang, Alan T., O’Sullivan, Jeremy A., Schleimer, Robert P., Tomasevic, Nenad, Bebbington, Christopher R., Bochner, Bruce S.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823959/
https://ncbi.nlm.nih.gov/pubmed/33374255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010019
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