Discovery, Function, and Therapeutic Targeting of Siglec-8

Siglecs (sialic acid-binding immunoglobulin-like lectins) are single-pass cell surface receptors that have inhibitory activities on immune cells. Among these, Siglec-8 is a CD33-related family member selectively expressed on human mast cells and eosinophils, and at low levels on basophils. These cel...

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Bibliographic Details
Published in:Cells
Main Authors: Youngblood, Bradford A., Leung, John, Falahati, Rustom, Williams, Jason, Schanin, Julia, Brock, Emily C., Singh, Bhupinder, Chang, Alan T., O’Sullivan, Jeremy A., Schleimer, Robert P., Tomasevic, Nenad, Bebbington, Christopher R., Bochner, Bruce S.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823959/
https://ncbi.nlm.nih.gov/pubmed/33374255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10010019
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