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Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes
The Myostatin/Activin branch of the TGF-β superfamily acts as a negative regulator of vertebrate skeletal muscle size, in part, through downregulation of insulin/insulin-like growth factor 1 (IGF-1) signaling. Surprisingly, recent studies in Drosophila indicate that motoneuron-derived Activin signal...
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| Publié dans: | Development |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists Ltd
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7823159/ https://ncbi.nlm.nih.gov/pubmed/33234715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.190868 |
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