The Drosophila TGF-beta/Activin-like ligands Dawdle and Myoglianin appear to modulate adult lifespan through regulation of 26S proteasome function in adult muscle

The Drosophila Activin signaling pathway employs at least three separate ligands – Activin-β (Actβ), Dawdle (Daw), and Myoglianin (Myo) – to regulate several general aspects of fruit fly larval development, including cell proliferation, neuronal remodeling, and metabolism. Here we provide experiment...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Langerak, Shaughna, Kim, Myung-Jun, Lamberg, Hannah, Godinez, Michael, Main, Mackenzie, Winslow, Lindsey, O'Connor, Michael B., Zhu, Changqi C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936056/
https://ncbi.nlm.nih.gov/pubmed/29615416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.029454
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