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Drosophila Activin signaling promotes muscle growth through InR/TORC1-dependent and -independent processes

The Myostatin/Activin branch of the TGF-β superfamily acts as a negative regulator of vertebrate skeletal muscle size, in part, through downregulation of insulin/insulin-like growth factor 1 (IGF-1) signaling. Surprisingly, recent studies in Drosophila indicate that motoneuron-derived Activin signal...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Kim, Myung-Jun, O'Connor, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823159/
https://ncbi.nlm.nih.gov/pubmed/33234715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.190868
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