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cAMP-Independent Activation of the Unfolded Protein Response by Cholera Toxin
Cholera toxin (CT) is an AB(5) protein toxin that activates the stimulatory alpha subunit of the heterotrimeric G protein (Gsα) through ADP-ribosylation. Activation of Gsα produces a cytopathic effect by stimulating adenylate cyclase and the production of cAMP. To reach its cytosolic Gsα target, CT...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822150/ https://ncbi.nlm.nih.gov/pubmed/33199355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00447-20 |
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