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Targeting Neuropilin-1 Suppresses the Stability of CD4(+) CD25(+) Regulatory T Cells via the NF-κB Signaling Pathway in Sepsis

Neuropilin-1 (Nrp-1) contributes to maintaining the stability of CD4(+) CD25(+) regulatory T cells (T(regs)). We investigated the impact of Nrp-1 on the stability of CD4(+) CD25(+) T(regs), and the underlying signaling pathways, in a model of sepsis. Splenic CD4(+) CD25(+) T(regs) were either treate...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Gao, Yu-lei, Wang, Chun-xue, Wang, Zi-yi, Li, Wen-jie, Liu, Yan-cun, Shou, Song-tao, Chai, Yan-fen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7822139/
https://ncbi.nlm.nih.gov/pubmed/33139385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00399-20
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