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Targeting Neuropilin-1 Suppresses the Stability of CD4(+) CD25(+) Regulatory T Cells via the NF-κB Signaling Pathway in Sepsis
Neuropilin-1 (Nrp-1) contributes to maintaining the stability of CD4(+) CD25(+) regulatory T cells (T(regs)). We investigated the impact of Nrp-1 on the stability of CD4(+) CD25(+) T(regs), and the underlying signaling pathways, in a model of sepsis. Splenic CD4(+) CD25(+) T(regs) were either treate...
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| Publicado no: | Infect Immun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822139/ https://ncbi.nlm.nih.gov/pubmed/33139385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00399-20 |
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