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Osteopontin regulates type I collagen fibril formation in bone tissue()

Osteopontin (OPN) is a non-collagenous protein involved in biomineralization of bone tissue. Beyond its role in biomineralization, we show that osteopontin is essential to the quality of collagen fibrils in bone. Transmission electron microscopy revealed that, in Opn(−/−) tissue, the organization of...

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Pubblicato in:Acta Biomater
Autori principali: Depalle, Baptiste, McGilvery, Catriona M., Nobakhti, Sabah, Aldegaither, Nouf, Shefelbine, Sandra J., Porter, Alexandra E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821990/
https://ncbi.nlm.nih.gov/pubmed/32344173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.04.040
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