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Osteopontin regulates type I collagen fibril formation in bone tissue()

Osteopontin (OPN) is a non-collagenous protein involved in biomineralization of bone tissue. Beyond its role in biomineralization, we show that osteopontin is essential to the quality of collagen fibrils in bone. Transmission electron microscopy revealed that, in Opn(−/−) tissue, the organization of...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Depalle, Baptiste, McGilvery, Catriona M., Nobakhti, Sabah, Aldegaither, Nouf, Shefelbine, Sandra J., Porter, Alexandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821990/
https://ncbi.nlm.nih.gov/pubmed/32344173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.04.040
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