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The Role of mTOR Inhibitors in Hematologic Disease: From Bench to Bedside
The mTOR pathway plays a central role in many cellular processes, such as cellular growth, protein synthesis, glucose, and lipid metabolism. Aberrant regulation of mTOR is a hallmark of many cancers, including hematological malignancies. mTOR inhibitors, such as Rapamycin and Rapamycin analogs (Rapa...
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| Publicado no: | Front Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7821787/ https://ncbi.nlm.nih.gov/pubmed/33489922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.611690 |
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