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mTOR signaling in glioblastoma: lessons learned from bench to bedside
Phosphatidyl-inositol-3 kinases (PI3Ks) constitute a family of intracellular lipid kinases that are frequently hyperactivated in glioblastoma. The PI3K complex links growth factor signaling with cellular proliferation, differentiation, metabolism, and survival. Mammalian target of rapamycin (mTOR) a...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940679/ https://ncbi.nlm.nih.gov/pubmed/20472883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq052 |
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