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mTOR signaling in glioblastoma: lessons learned from bench to bedside
Phosphatidyl-inositol-3 kinases (PI3Ks) constitute a family of intracellular lipid kinases that are frequently hyperactivated in glioblastoma. The PI3K complex links growth factor signaling with cellular proliferation, differentiation, metabolism, and survival. Mammalian target of rapamycin (mTOR) a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2940679/ https://ncbi.nlm.nih.gov/pubmed/20472883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq052 |
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