Kcnj16 knockout produces audiogenic seizures in the Dahl salt-sensitive rat

K(ir)5.1 is an inwardly rectifying potassium (K(ir)) channel subunit abundantly expressed in the kidney and brain. We previously established the physiologic consequences of a Kcnj16 (gene encoding K(ir)5.1) knockout in the Dahl salt-sensitive rat (SS(Kcnj16–/–)), which caused electrolyte/pH dysregul...

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Vydáno v:JCI Insight
Hlavní autoři: Manis, Anna D., Palygin, Oleg, Isaeva, Elena, Levchenko, Vladislav, LaViolette, Peter S., Pavlov, Tengis S., Hodges, Matthew R., Staruschenko, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821607/
https://ncbi.nlm.nih.gov/pubmed/33232300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143251
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