Genetic mutation of Kcnj16 identifies Kir5.1-containing channels as key regulators of acute and chronic pH homeostasis

Acute and chronic homeostatic pH regulation is critical for the maintenance of optimal cellular function. Renal mechanisms dominate global pH regulation over longer time frames, and rapid adjustments in ventilation compensate for acute pH and CO(2) changes. Ventilatory CO(2) and pH chemoreflexes are...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Puissant, Madeleine M., Muere, Clarissa, Levchenko, Vladislav, Manis, Anna D., Martino, Paul, Forster, Hubert V., Palygin, Oleg, Staruschenko, Alexander, Hodges, Matthew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436665/
https://ncbi.nlm.nih.gov/pubmed/30605394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802257R
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