Essential role of K(ir)5.1 channels in renal salt handling and blood pressure control

Supplementing diets with high potassium helps reduce hypertension in humans. Inwardly rectifying K(+) channels K(ir)4.1 (Kcnj10) and K(ir)5.1 (Kcnj16) are highly expressed in the basolateral membrane of distal renal tubules and contribute to Na(+) reabsorption and K(+) secretion through the direct c...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Palygin, Oleg, Levchenko, Vladislav, Ilatovskaya, Daria V., Pavlov, Tengis S., Pochynyuk, Oleh M., Jacob, Howard J., Geurts, Aron M., Hodges, Matthew R., Staruschenko, Alexander
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621918/
https://ncbi.nlm.nih.gov/pubmed/28931751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92331
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