Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats

In the kidney, reabsorption via the epithelial sodium channel (ENaC) is involved in long-term blood pressure control. Previously we demonstrated that ENaC hyperactivity is associated with development of salt-sensitive (SS) hypertension in Dahl SS rats. AMP-activated kinase (AMPK), playing a role in...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Pavlov, Tengis S., Levchenko, Vladislav, Ilatovskaya, Daria V., Li, Hui, Palygin, Oleg, Pastor-Soler, Nuria M., Hallows, Kenneth R., Staruschenko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397526/
https://ncbi.nlm.nih.gov/pubmed/28473772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00227
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