LRP1-mediated pH-sensitive polymersomes facilitate combination therapy of glioblastoma in vitro and in vivo

BACKGROUND: Glioblastoma (GBM) is the most invasive primary intracranial tumor, and its effective treatment is one of the most daunting challenges in oncology. The blood–brain barrier (BBB) is the main obstacle that prevents the delivery of potentially active therapeutic compounds. In this study, a...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: He, Chen, Zhang, Zhiyuan, Ding, Yinan, Xue, Kangli, Wang, Xihui, Yang, Rui, An, Yanli, Liu, Dongfang, Hu, Chunmei, Tang, Qiusha
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821499/
https://ncbi.nlm.nih.gov/pubmed/33482822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00751-x
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