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LRP1-mediated pH-sensitive polymersomes facilitate combination therapy of glioblastoma in vitro and in vivo

BACKGROUND: Glioblastoma (GBM) is the most invasive primary intracranial tumor, and its effective treatment is one of the most daunting challenges in oncology. The blood–brain barrier (BBB) is the main obstacle that prevents the delivery of potentially active therapeutic compounds. In this study, a...

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Bibliografische gegevens
Gepubliceerd in:J Nanobiotechnology
Hoofdauteurs: He, Chen, Zhang, Zhiyuan, Ding, Yinan, Xue, Kangli, Wang, Xihui, Yang, Rui, An, Yanli, Liu, Dongfang, Hu, Chunmei, Tang, Qiusha
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821499/
https://ncbi.nlm.nih.gov/pubmed/33482822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00751-x
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