LRP1-mediated pH-sensitive polymersomes facilitate combination therapy of glioblastoma in vitro and in vivo

BACKGROUND: Glioblastoma (GBM) is the most invasive primary intracranial tumor, and its effective treatment is one of the most daunting challenges in oncology. The blood–brain barrier (BBB) is the main obstacle that prevents the delivery of potentially active therapeutic compounds. In this study, a...

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Publicado en:J Nanobiotechnology
Autores principales: He, Chen, Zhang, Zhiyuan, Ding, Yinan, Xue, Kangli, Wang, Xihui, Yang, Rui, An, Yanli, Liu, Dongfang, Hu, Chunmei, Tang, Qiusha
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821499/
https://ncbi.nlm.nih.gov/pubmed/33482822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-020-00751-x
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