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R-Spondins 2 and 3 Are Overexpressed in a Subset of Human Colon and Breast Cancers

Wnt signaling is activated in many cancer types, yet targeting the canonical Wnt pathway has been challenging for cancer therapy. The pathway might be effectively targeted at many levels depending on the mechanism by which it has become hyperactive. Recently, mouse genetic screens have found that R-...

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Détails bibliographiques
Publié dans:DNA Cell Biol
Auteurs principaux: Conboy, Caitlin B., Vélez-Reyes, Germán L., Rathe, Susan K., Abrahante, Juan E., Temiz, Nuri A., Burns, Michael B., Harris, Reuben S., Starr, Timothy K., Largaespada, David A.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc., publishers 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821429/
https://ncbi.nlm.nih.gov/pubmed/33320737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2020.5585
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