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Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons

The focal and progressive degeneration of dopaminergic (DA) neurons in ventral midbrain has made Parkinson's disease (PD) a particularly interesting target of cell-based therapies. However, ethical issues and limited tissue availability have so far hindered the widespread use of human fetal tis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Heliyon
Hauptverfasser: Fiorenzano, Alessandro, Birtele, Marcella, Wahlestedt, Jenny Nelander, Parmar, Malin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821040/
https://ncbi.nlm.nih.gov/pubmed/33532642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06006
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