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Hemolysis inhibits humoral B-cell responses and modulates alloimmunization risk in patients with sickle cell disease
Red blood cell alloimmunization remains a barrier for safe and effective transfusions in sickle cell disease (SCD), but the associated risk factors remain largely unknown. Intravascular hemolysis, a hallmark of SCD, results in the release of heme with potent immunomodulatory activity, although its e...
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| 出版年: | Blood |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7820872/ https://ncbi.nlm.nih.gov/pubmed/33152749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020008511 |
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