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Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization

Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known. Given the chronic hemolytic state characteristic of sickl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Haematologica
Hauptverfasser: Godefroy, Emmanuelle, Liu, Yunfeng, Shi, Patricia, Mitchell, W. Beau, Cohen, Devin, Chou, Stella T., Manwani, Deepa, Yazdanbakhsh, Karina
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5060019/
https://ncbi.nlm.nih.gov/pubmed/27229712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.147181
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