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Probabilistic colocalization of genetic variants from complex and molecular traits: promise and limitations

Colocalization analysis has emerged as a powerful tool to uncover the overlapping of causal variants responsible for both molecular and complex disease phenotypes. The findings from colocalization analysis yield insights into the molecular pathways of complex diseases. In this paper, we conduct an i...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Hukku, Abhay, Pividori, Milton, Luca, Francesca, Pique-Regi, Roger, Im, Hae Kyung, Wen, Xiaoquan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820626/
https://ncbi.nlm.nih.gov/pubmed/33308443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.11.012
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