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Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus

Type 1 diabetes mellitus (T1DM) is associated with low bone mass and a higher risk for fractures. Dickkopf-1 (Dkk1), which inhibits Wnt signaling, osteoblast function, and bone formation, has been found to be increased in the serum of patients with T1DM. Here, we investigated the functional role of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hildebrandt, Nick, Colditz, Juliane, Dutra, Caio, Goes, Paula, Salbach-Hirsch, Juliane, Thiele, Sylvia, Hofbauer, Lorenz C., Rauner, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820472/
https://ncbi.nlm.nih.gov/pubmed/33479403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81543-7
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